Enforcement of Textbook Orthodoxy Annals: Xist Gene X-ed
In "Re-Write The Textbooks: Key Genetic Phenomenon Shown To Be Different Than Believed," (ScienceDaily, July 2, 2009) we learn,
Because females carry two copies of the X chromosome to males’ one X and one Y, they harbor a potentially toxic double dose of the over 1000 genes that reside on the X chromosome.Hope no careers went down on account of doubt on this point ...
To compensate for this imbalance, mammals such as mice and humans shut down one entire X-chromosome through a phenomenon known as X-inactivation. For almost two decades, researchers have believed that one particular gene, called Xist, provides the molecular trigger of X-inactivation.
Now, a new UNC study appearing online July 1 in the journal Nature disputes the current dogma by showing that this process can occur even in the absence of this gene.